Article
Study of dosage compensation in Drosophila.
Genetics - 1 Nov 2003
Chiang Pei-Wen, Kurnit David M
Abstract excerpt
Using a sensitive RT-QPCR assay, we analyzed the regulatory effects of sex and different dosage compensation mutations in Drosophila. To validate the assay, we showed that regulation for several genes indeed varied with the number of functional copies of that gene. We then confirmed that dosage compensation occurred for most genes we examined in male and female flies. Finally, we examined the effects on...
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