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Article

In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations.

Carcinogenesis - 1 Sept 1994

Mangold K A, Hubchak S, Mangino M M, Laconi S, Scarpelli D G

Abstract excerpt

Neoplastic transformation of Syrian golden hamster (SGH) pancreatic duct cells was induced by in vitro treatment with the direct-acting carcinogens N-methylnitrosourea (MNU) and N-(2-hydroxypropyl)nitrosourea (HPNU), with subsequent selection by sustained culture in serum- and epidermal growth factor (EGF)-deprived medium. The present study examines the efficacy of serum and EGF deprivation as a selection...

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PMID: 7923593
DOI: 10.1093/carcin/15.9.1979

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EGF

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In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations.PMID 7923593Read ↗

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