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Article

In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations.

Carcinogenesis - 1 Sept 1994

Mangold K A, Hubchak S, Mangino M M, Laconi S, Scarpelli D G

Abstract excerpt

Neoplastic transformation of Syrian golden hamster (SGH) pancreatic duct cells was induced by in vitro treatment with the direct-acting carcinogens N-methylnitrosourea (MNU) and N-(2-hydroxypropyl)nitrosourea (HPNU), with subsequent selection by sustained culture in serum- and epidermal growth fa...

Topics

Animals
Base Sequence
Carcinogens
Cell Transformation, Neoplastic
Cells, Cultured
Cricetinae
Gene Expression
Genes, ras
Mesocricetus
Methylnitrosourea
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nitrosourea Compounds

Pancreatic Ducts

Pancreatic Neoplasms

Time Factors

Transforming Growth Factor alpha

Source

Identifiers

PMID: 7923593
DOI: 10.1093/carcin/15.9.1979

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7923593-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations.PMID 7923593Read ↗

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