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Article

Alterations in the Smad4 gene in hamster pancreatic duct adenocarcinomas and established cell lines.

Oncology reports - 1 Jul 2006

Shimizu Kyoko, Kitahashi Tsukasa, Fujii Hiromasa, Tsutsumi Masahiro, Mori Toshio, Honoki Kanya, Tsujiuchi Toshifumi

Abstract excerpt

Alterations of the Smad4 gene, identified as a mediator of the transforming growth factor-beta pathway, were investigated in hamster pancreatic duct adenocarcinomas (PDAs) and established cell lines. Female Syrian golden hamsters received 70 mg/kg of N-nitrosobis(2-oxopropyl)amine (BOP) followed by repeated exposure to an augmentation pressure regimen consisting of a choline-deficient diet combined with...

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PMID: 16786127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Alterations in the Smad4 gene in hamster pancreatic duct adenocarcinomas and established cell lines.PMID 16786127Read ↗

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