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Article

Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters.

Pancreas - 1 Apr 1998

Konishi Y, Tsutsumi M, Tsujiuchi T

Abstract excerpt

In this article, we introduce our rapid-production model for pancreatic duct adenocarcinomas and describe the mechanisms of pancreatic duct carcinogenesis so far elucidated in Syrian golden hamsters. It is evident that a series of histogenetic steps are involved, leading from hyperplasia through atypical hyperplasia to intraductal carcinoma and invasive carcinoma. As DNA alters, K-ras mutation appears to be an...

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PMID: 9548670
DOI: 10.1097/00006676-199804000-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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