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Article

Analysis of the tumor suppressor gene p53 in xeroderma pigmentosum fibroblasts.

Cancer letters - 30 Sept 1994

Lavu S, Srivastava M, Srivastava S K

Abstract excerpt

Genetic risk factor(s) for skin cancers have been described in patients with xeroderma pigmentosum (XP). The tumor suppressor gene, p53, is one of the most frequently mutated genes found in human tumors. To evaluate the role of XP-related genetic defects in the p53 gene, skin fibroblast cell lines derived from XP donors were analysed for mutations in exons 5-9 (the regions of gene highly susceptible for...

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Identifiers

PMID: 7923108
DOI: 10.1016/0304-3835(94)90232-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Analysis of the tumor suppressor gene p53 in xeroderma pigmentosum fibroblasts.PMID 7923108Read ↗

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Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas.Semantic proximity Read ↗

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Absence of p53 gene mutations in cutaneous melanoma.Semantic proximity Read ↗

Far less frequent mutations in ras genes than in the p53 gene in skin tumors of xeroderma pigmentosum patients.Semantic proximity Read ↗

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Ultraviolet-specific mutations in p53 gene in skin tumors in xeroderma pigmentosum patients.Semantic proximity Read ↗

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