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Article

Detection of high incidence of H-RAS oncogene point mutations in acute myelogenous leukemia.

American journal of hematology - 1 Jun 1993

Imamura N, Kuramoto A, Ishihara H, Shimizu S

Abstract excerpt

We have been analyzing RAS p21 proteins and the DNA sequence of leukemic cells. We report here that these cells have high expression of H-RAS p21, which originates from point mutations of RAS oncogenes. The leukemic cells from six patients with acute myelogenous leukemia were separated from hepar...

Topics

Base Sequence
DNA, Neoplasm
Flow Cytometry
Genes, ras
Humans
Leukemia, Myeloid, Acute
Molecular Sequence Data
Oncogene Protein p21(ras)
Phenotype
Point Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7916576
DOI: 10.1002/ajh.2830430217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7916576-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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