Article
Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study.
Lancet (London, England) - 30 Jul 1994
Heym B, Honoré N, Truffot-Pernot C, Banerjee A, Schurra C, Jacobs W R, van Embden J D, Grosset J H, Cole S T
Abstract excerpt
Tuberculosis-control programmes are compromised by the increased frequency of multidrug-resistant strains of Mycobacterium tuberculosis. We used the polymerase chain reaction (PCR) and single-strand conformation polymorphism (SSCP) analysis techniques to establish the molecular basis of resistance in 37 drug-resistant isolates of M tuberculosis, and correlated these findings with clinical and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.