Article
[Clinical application and evaluation of the detection of five drugs resistance genes in Mycobacterium tuberculosis].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Nov 2002
Wang Wei, Li Hongmin, Wu Xueqiong, Wang Ansheng, Wang Zhongyuan, Liu Jinwei, Chen Hongbing, Lin Minggui, Wang Jinhe, Ye Yixiu, Li Sumei
Abstract excerpt
OBJECTIVE: To evaluate the clinical application of the detection of the drug resistant genes rPOB, katG, rPSL, PncA and embB in M. tuberculosis by using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) analysis. METHODS: Gene mutations and anti-tuberculous drug susceptibility test were analyzed in 109 M. tuberculosis isolates by PCR-SSCP and the proportion method on Lowenstein-Jensen...
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