Antimicrobial agent resistance in mycobacteria: molecular genetic insights.

doi:10.1128/CMR.8.4.496

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Article

Antimicrobial agent resistance in mycobacteria: molecular genetic insights.

Clinical microbiology reviews - 1 Oct 1995

Musser J M

Abstract excerpt

The primary theme emerging from molecular genetic work conducted with Mycobacterium tuberculosis and several other mycobacterial species is that resistance is commonly associated with simple nucleotide alterations in target chromosomal genes rather than with acquisition of new genetic elements en...

Topics

Amino Acid Sequence
Anti-Infective Agents
Antibiotics, Antitubercular
Base Sequence
Drug Resistance, Microbial
Fluoroquinolones
Genes, Bacterial
Isoniazid
Molecular Sequence Data
Mutation
Mycobacterium

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