Article

Antimicrobial agent resistance in mycobacteria: molecular genetic insights.

1995-01-01

Abstract excerpt

The primary theme emerging from molecular genetic work conducted with Mycobacterium tuberculosis and several other mycobacterial species is that resistance is commonly associated with simple nucleotide alterations in target chromosomal genes rather than with acquisition of new genetic elements encoding antibiotic-altering enzymes. Mutations in an 81-bp region of the gene (rpoB) encoding the beta subunit of RNA pol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fb1cd6a2-55e6-54b6-afe5-5149f8bbe5ed
DOI: 10.1128/cmr.8.4.496-514.1995

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antimicrobial agent resistance in mycobacteria: molecular genetic insights.DOI 10.1128/cmr.8.4.496-514.1995Read

Antimicrobial agent resistance in mycobacteria: molecular genetic insights.Semantic proximity Read

Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update.Semantic proximity Read

Molecular mechanisms of multiple drug resistance in clinical isolates of Mycobacterium tuberculosis.Semantic proximity Read

Molecular Mechanisms Underlying Antimicrobial Resistance in Mycobacteria.Semantic proximity Read

Characterization of rifampin-resistance in pathogenic mycobacteria.Semantic proximity Read

Molecular genetic methods for diagnosis and antibiotic resistance detection of mycobacteria from clinical specimensSemantic proximity Read

Molecular determinants of drug resistance in tuberculosis.Semantic proximity Read

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis.Semantic proximity Read

Investigation of Gene Regions Responsible for Drug Resistance in Clinical Isolates of Mycobacterium tuberculosis Complex Resistant to at Least Two First-Line Anti-Tuberculosis Drugs.Semantic proximity Read

Molecular mechanisms of drug resistance in Mycobacterium tuberculosis clinical isolates.Semantic proximity Read

Clinical implications of molecular drug resistance testing for <I>Mycobacterium tuberculosis</I>: a TBNET/RESIST-TB consensus statementSemantic proximity Read

[Molecular identification of mycobacteria and detection of antibiotic resistance].Semantic proximity Read