Article
[The studies on the molecular mechanism of rifampin-resistant Mycobacterium tuberculosis].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Dec 2000
Zhuang Y, He X, Zhang X
Abstract excerpt
OBJECTIVE: To evaluate the molecular mechanism of rifampin (RFP)-resistance of M. tuberculosis, and to provide evidence of molecular genetics for basic and clinical research of tuberculosis. METHODS: rpoB gene mutation of M. tuberculosis was detected with PCR-SSCP from 262 clinical isolates, including 74 drug sensitive strains, and 188 RFP-resistant only or multiple drug-resistant strains of M. tuberculosis,...
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