Article
Genome and MIC stability in Mycobacterium tuberculosis and indications for continuation of use of isoniazid in multidrug-resistant tuberculosis.
Journal of medical microbiology - 1 Oct 1997
Victor T C, Warren R, Butt J L, Jordaan A M, Felix J V, Venter A, Sirgel F A, Schaaf H S, Donald P R, Richardson M, Cynamon M H, Van Helden P D
Abstract excerpt
Mycobacterium tuberculosis strains resistant to two or more of the first line antituberculosis drugs (MDR) are a serious threat to successful tuberculosis control programmes. For this retrospective study, 85 follow-up drug resistant isolates from 23 patients residing in a community with a high incidence of tuberculosis were collected and the level of in-vitro resistance to antibiotics determined quantitatively....
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