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Article

Genetic linkage of familial expansile osteolysis to chromosome 18q

1 Jan 1994

Abstract excerpt

Familial expansile osteolysis is a rare bone dysplasia which is transmitted as an autosomal dominant trait in a large kindred in Northern Ireland. The gene which causes the disease shows tight linkage with several polymorphic markers on chromosome 18q with a maximum lod score of 11.53 at a recombination fraction of 0.00 with D18S64. The gene is flanked by D18S35 and D18S61 and is located at chromosome...

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PMID: 7911698
DOI: 10.1093/hmg/3.2.359

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