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Article

Familial Paget's disease of bone: nonlinkage to the PDB1 and PDB2 loci on chromosomes 6p and 18q in a large pedigree.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2001

Good D, Busfield F, Duffy D, Lovelock P K, Kesting J B, Cameron D P, Shaw J T

Abstract excerpt

Paget's disease of bone is a common condition characterized by bone pain, deformity, pathological fracture, and an increased incidence of osteosarcoma. Genetic factors play a role in the pathogenesis of Paget's disease but the molecular basis remains largely unknown. Susceptibility loci for Paget's disease of bone have been mapped to chromosome 6p21.3 (PDB1) and 18q21.1-q22 (PDB2) in different pedigrees. We have...

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PMID: 11149487
DOI: 10.1359/jbmr.2001.16.1.33

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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