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Article

Common mechanisms of osteosarcoma and paget's disease

1 Nov 1999

Abstract excerpt

One of the most serious complications of Paget's disease is a significant increase in the incidence of osteosarcoma. Approximately 1% of Paget's patients develop osteosarcoma, an increase in risk that is several thousand-fold higher than the general population. This risk contributes significantly to the mortality and morbidity of Paget's disease patients. We examined several cases of pagetic and sporadic...

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PMID: 10510212
DOI: 10.1002/jbmr.5650140209

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Common mechanisms of osteosarcoma and paget's diseasePMID 10510212Read ↗

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Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma.Semantic proximity Read ↗

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