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Article

Localization of the gene for fibrodysplasia ossificans progressiva (FOP) to chromosome 17q21-22.

Genetic counseling (Geneva, Switzerland) - 1 Jan 2000

Lucotte G, Bathelier C, Mercier G, Gérard N, Lenoir G, Sémonin O, Fontaine K

Abstract excerpt

Fibrodysplasia ossificans progressiva (FOP) is a very rare disease characterized by congenital malformation of the great toes and progressive heterotopic ossification of muscles. To identify the chromosomal localization of the FOP gene, we conducted a genomewide linkage analysis using seven affected families. The FOP phenotype is linked to markers located in the 17q21-22 region (LOD score of 3.41 at the...

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PMID: 11140409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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