Article
Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group.
Neurology - 8 Feb 2000
Steckley J L, Dyment D A, Sadovnick A D, Risch N, Hayes C, Ebers G C
Abstract excerpt
The objective of this study was to investigate genes involved in the metabolism and function of vitamin D as candidate genes for genetic susceptibility to MS. Restriction fragment length polymorphisms and highly polymorphic microsatellite markers within or very close to the 1,25(OH)2D3 receptor (VDR) [12q14], the vitamin D binding protein (DBP) [4q12], and the 25(OH)D2 1alpha-hydroxylase [12q13] loci were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
