Evidence of allelic imbalance of chromosome 6 in human astrocytomas.

doi:10.1212/wnl.44.3_part_1.533

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Article

Evidence of allelic imbalance of chromosome 6 in human astrocytomas.

Neurology - 1 Mar 1994

Liang B C, Ross D A, Greenberg H S, Meltzer P S, Trent J M

Abstract excerpt

Transfer of human chromosome 6 can suppress the malignant phenotype of melanoma. Because of the neural ectoderm origin of melanoma and since up to 30% of gliomas have abnormalities involving chromosome 6, we performed restriction fragment length polymorphism analysis to determine the importance o...

Topics

Alleles
Astrocytoma
Blotting, Southern
Brain Neoplasms
Chromosome Deletion
Chromosomes, Human, Pair 6
DNA Probes
DNA, Neoplasm
Ganglioglioma
Humans
Polymorphism, Restriction Fragment Length

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