Identification of allelic loss on chromosome arm 6p in human astrocytomas by arbitrarily primed polymerase chain reaction.

doi:10.1002/(sici)1098-2264(199807)22:3<165::aid-gcc1>3.0.co;2-u

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Article

Identification of allelic loss on chromosome arm 6p in human astrocytomas by arbitrarily primed polymerase chain reaction.

Genes, chromosomes & cancer - 1 Jul 1998

Saitoh Y, Bruner J M, Levin V A, Kyritsis A P

Abstract excerpt

We employed the arbitrarily primed polymerase chain reaction (AP-PCR), which is a PCR-based genomic fingerprinting technique, to detect novel genetic alterations in human astrocytomas. DNA fingerprints generated by arbitrary primers were compared in normal lymphocytes and tumor tissues from the s...

Topics

Alleles
Astrocytoma
Chromosome Deletion
Chromosomes, Human, Pair 6
Cyclin-Dependent Kinase Inhibitor p21
Cyclins
Exons
Genetic Markers
Glioma
Humans
Microsatellite Repeats
Polymerase Chain Reaction

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