T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.

doi:10.1002/art.1780370117

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Article

T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.

Arthritis and rheumatism - 1 Jan 1994

Mountz J D, Zhou T, Long R E, Bluethmann H, Koopman W J, Edwards C K

Abstract excerpt

OBJECTIVE: To define the influence of the T cell receptor (TCR) and the lpr autoimmune gene on the induction and progression of superantigen-induced arthritis in V beta 8 transgenic MRL-lpr/lpr mice. METHODS: The time to onset and the extent of synovial hyperplasia after the induction of arthriti...

Topics

Animals
Arthritis, Rheumatoid
CD4-Positive T-Lymphocytes
Disease Models, Animal
Enterotoxins
Humans
Immunoglobulin G
Immunoglobulins
Injections, Intra-Articular
Knee Joint
Mice
Mice, Transgenic
Phenotype
Receptors, Antigen, T-Cell
Superantigens
Synovial Fluid
T-Lymphocytes
Weight Loss

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Open in PubMed

Identifiers

PMID: 7907476
DOI: 10.1002/art.1780370117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7907476-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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