Control of the rat T cell response to retroviral and bacterial superantigens by class II MHC products and Tcrb-V8.2 alleles.

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Article

Control of the rat T cell response to retroviral and bacterial superantigens by class II MHC products and Tcrb-V8.2 alleles.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 1994

Herrmann T, Hochgrebe T, Torres-Nagel N E, Huber B T, Hünig T

Abstract excerpt

The in vitro response of unprimed rat T cells to retroviral and bacterial superantigens (SAg) was analyzed with TCR V beta 8.2-, 8.5-, 10-, and 16-specific mAbs. Specific stimulation of V beta 8.2 and 8.5 CD4 cells was observed in the response to Mls1a, the retroviral SAg encoded by integrated provirus Mtv-7 (Mtv-7 SAg), which was presented by mouse B cells or mouse fibroblasts transfected with DR1 genes and the...

Topics

Alleles
Animals
Antigen Presentation
Antigens, Bacterial
Antigens, Viral
Base Sequence
DNA Primers
Enterotoxins
Female
Histocompatibility Antigens Class II
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocyte Activation

Male

Mice

Mice, Inbred Strains

Molecular Sequence Data

Rats

Rats, Inbred Lew

Source

Open in PubMed

Identifiers

PMID: 8157953

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8157953-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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