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Article

Search for oncogene mutations in X-ray-transformed mouse 10T1/2 cells by denaturing gradient gel electrophoresis blotting.

International journal of radiation biology - 1 Feb 1994

Krolewski B, Little J B

Abstract excerpt

We have sought evidence for possible mutations within the c-myc, c-Ha-ras and c-Ki-ras loci of X-ray-transformed mouse C3H10T1/2 cell clones using the denaturing gradient gel electrophoresis (DGGE) blot technique. This highly sensitive method was developed to detect any mutations (e.g. single bas...

Topics

Animals
Cell Line
Cell Transformation, Neoplastic
Electrophoresis, Agar Gel
Genes, myc
Genes, ras
Mice
Mutation
Nucleic Acid Denaturation
Oncogenes
X-Rays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7907112
DOI: 10.1080/09553009414550181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7907112-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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