Enhanced expression of EGF receptor and low frequency of ras mutations in X-ray-induced rat thyroid tumours.

doi:10.1007/pl00008191

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Enhanced expression of EGF receptor and low frequency of ras mutations in X-ray-induced rat thyroid tumours.

Virchows Archiv : an international journal of pathology - 1 Oct 1999

Haugen D R, Lillehaug J R, Akslen L A

Abstract excerpt

Radiation is recognized as a carcinogenic factor for the thyroid gland. In this experimental study, oncogene expression was investigated in radiation-induced rat thyroid tumours. Forty 3-month-old Wistar rats received X-ray-irradiation to the neck region; 40 animals were untreated controls. After 14 months, thyroid tumours had developed in 25 of the 29 irradiated animals still alive; 76% of these tumours were...

Topics

Animals
DNA Mutational Analysis
ErbB Receptors
Female
Genes, ras
Immunohistochemistry
Male
Mutation
Neoplasms, Radiation-Induced
RNA, Messenger
Rats
Rats, Wistar
Thyroid Neoplasms
X-Rays

Source

Open in PubMed

Identifiers

PMID: 10526008
DOI: 10.1007/pl00008191

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics