Article
Mutation of RAS oncogene in atomic bomb radiation-exposed leukemia.
Journal of radiation research - 1 Dec 1991
Tanaka K, Takechi M, Kamada N
Abstract excerpt
To determine what the role of RAS oncogene is in radiation-induced leukemia, we investigated the frequency of mutations and the sites of the base substitution of activated N- and K-RAS oncogenes in 25 leukemic patients who had been exposed to the atomic bomb and compared the results with those for 47 non-exposed leukemic patients. To detect the presence of mutated RAS oncogene, we used the PCR method to analyze...
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