Altered oncogenes in UV-transformed C3H 10T1/2 mouse cells: identification of mutated H-ras allele(s).

doi:10.1080/09553009114550021

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Article

Altered oncogenes in UV-transformed C3H 10T1/2 mouse cells: identification of mutated H-ras allele(s).

International journal of radiation biology - 1 Jan 1991

Thomas J E, Guernsey D L

Abstract excerpt

Ultraviolet (UV) light will transform mammalian cells in culture to a phenotype which is characteristic of in vivo neoplasia. The UV-transformed C3H 10T1/2 mouse cell lines, TU-2 and TU-3, were analysed to determine the molecular mechanisms which may account for their phenotype, and to determine...

Topics

Alleles
Animals
Blotting, Northern
Blotting, Southern
Cell Line, Transformed
Cell Transformation, Neoplastic
Genes, ras
In Vitro Techniques
Methylation
Mice
Mutation
Ultraviolet Rays

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