Article
Allelic loss of chromosome 17p in urothelial cancer: strong association with invasive phenotype.
The Journal of urology - 1 Nov 1992
Habuchi T, Ogawa O, Kakehi Y, Ogura K, Koshiba M, Sugiyama T, Yoshida O
Abstract excerpt
Allelic loss of chromosome 17p with a mutated p53 gene on the remaining allele has been observed in various kinds of human cancers. To examine the significance of allelic loss of chromosome 17p in human urothelial cancer with special attention to the clinicopathological features, 49 tumors with various stages and grades from 43 cases (35 bladder cancers and 8 renal pelvic or ureteral cancers) were examined for...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Carcinoma, Transitional Cell
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Female
- Genetic Markers
- Heterozygote
- Humans
