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Article

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia.

Genes, chromosomes & cancer - 1 Sept 2008

Fabris Sonia, Mosca Laura, Todoerti Katia, Cutrona Giovanna, Lionetti Marta, Intini Daniela, Matis Serena, Colombo Monica, Agnelli Luca, Gentile Massimo, Spriano Mauro, Callea Vincenzo, Festini Gianluca, Molica Stefano, Lambertenghi Deliliers Giorgio, Morabito Fortunato, Ferrarini Manlio, Neri Antonino

Abstract excerpt

Distinct genetic abnormalities, such as TP53 deletion at 17p13.1, have been identified as having adverse prognostic relevance in B-cell chronic lymphocytic leukemia (B-CLL), and conventional cytogenetic studies have shown that TP53 deletion in B-CLL is mainly associated with the loss of 17p due to complex chromosomal rearrangements. We used an integrative genomic approach to investigate the significance of 17p...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, p53

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Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Identifiers

PMID: 18521849
DOI: 10.1002/gcc.20579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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