Numeric aberration of chromosome 17 is strongly correlated with p53 overexpression, tumor proliferation and histopathology in human bladder cancer.

doi:10.1111/j.1442-2042.1998.tb00358.x

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Article

Numeric aberration of chromosome 17 is strongly correlated with p53 overexpression, tumor proliferation and histopathology in human bladder cancer.

International journal of urology : official journal of the Japanese Urological Association - 1 Jul 1998

Li B, Kanamaru H, Noriki S, Fukuda M, Okada K

Abstract excerpt

BACKGROUND: This study investigated the relationships between the numeric aberrations of chromosome 17 and p53 expression, the proliferating cell nuclear antigen labeling index (PCNA-LI) and histopathology, to determine their prognostic significance in bladder cancer. METHODS: Using in situ hybri...

Topics

Aged
Aged, 80 and over
Centromere
Chromosome Aberrations
Chromosomes, Human, Pair 17
Female
Gene Expression Regulation, Neoplastic
Humans
In Situ Hybridization
Interphase
Male
Middle Aged
Neoplasm Staging
Phenotype
Prognosis
Proliferating Cell Nuclear Antigen
Survival Analysis
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 9712438
DOI: 10.1111/j.1442-2042.1998.tb00358.x

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9712438-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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