Article
Superimposed histologic and genetic mapping of chromosome 17 alterations in human urinary bladder neoplasia.
Oncogene - 1 May 1997
Chaturvedi V, Li L, Hodges S, Johnston D, Ro J Y, Logothetis C, von Eschenbach A C, Batsakis J G, Czerniak B
Abstract excerpt
Multistep alterations of chromosome 17 in the progression of human urinary bladder neoplasia were studied by superimposed histologic and genetic mapping. The p53 gene was included in the analysis as a model tumor suppressor gene that is frequently involved in urothelial carcinogenesis. The strate...
Topics
- Alleles
- Carcinoma, Transitional Cell
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Cocarcinogenesis
- DNA, Neoplasm
- Disease Progression
- Female
- Gene Deletion
- Genes, p53
- Genetic Markers
- Humans
- Lod Score
- Male
- Mucous Membrane
- Neoplasm Invasiveness
- Precancerous Conditions
- Urinary Bladder