Article
c-Ha-ras BamHI RFLP in human urothelial tumors and point mutations in hot codons.
Neoplasma - 1 Jan 1993
Weismanová E, Kalúz S, Skorvaga M
Abstract excerpt
High-molecular-weight DNAs from 30 bladder and renal cell carcinomas (RCC) were isolated and the c-Ha-ras gene BamHI RFLP was examined. Amplification of c-Ha-ras with normal localization with regard to the size of alleles was found only in one case. One of the normally localized c-Ha-ras allele t...
Topics
- Alleles
- Base Sequence
- Blotting, Southern
- Carcinoma, Renal Cell
- Cloning, Molecular
- Codon
- DNA, Neoplasm
- Deoxyribonuclease BamHI
- Escherichia coli
- Genes, ras
- Genomic Library
- Humans
- Kidney Neoplasms
- Molecular Sequence Data
- Point Mutation
- Polymorphism, Restriction Fragment Length
- Restriction Mapping
- Urinary Bladder Neoplasms
