Restriction fragment length polymorphism and activation of c-Ha-ras gene in urothelial cancer.

Article

Restriction fragment length polymorphism and activation of c-Ha-ras gene in urothelial cancer.

Anticancer research - 1 Jan 2000

Ishikawa J, Maeda S, Kamidono S, Sugiyama T

Abstract excerpt

The human c-Ha-ras gene shows restriction length polymorphism (RFLP) due to the variable tandem repetition (VTR) of DNA sequences in the 3'-flanking region. It was suggested that RFLP of the c-Ha-ras gene may be useful in detecting individuals at risk of cancer. In vitro studies showed transcript...

Topics

Base Sequence
Gene Expression Regulation
Humans
Molecular Sequence Data
Mutation
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Proto-Oncogenes
Urinary Bladder Neoplasms

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