Article
[A molecular genetic analysis of the 12th codon of the Ha-ras-1 proto-oncogene in human carcinoma and stomach ulcer cells].
Eksperimental'naia onkologiia - 1 Jan 1990
Novikov L B, Fedorov S N, Iatsuk O S, Kalinovskiĭ V P, Tlevlesov N Ia, Levanova G I, Matveev B V, Mel'nikov R A, Seĭts I F
Abstract excerpt
A method of the restriction analysis by Msp I enzyme has been used to analyze the 12th codon of Ha-ras-1 protooncogene in 10 human carcinomas and in the stomach mucosa adjacent to them their 5 metastases into the regional lymph nodes and in 2 ulcers. No point mutation was found.
Topics
- Adenocarcinoma
- Codon
- DNA
- DNA, Neoplasm
- Genes, ras
- Humans
- Lymphatic Metastasis
- Molecular Biology
- Mutation
- Proto-Oncogene Mas
- Proto-Oncogenes
- RNA, Messenger
