Article
Denaturing gradient gel electrophoretic analysis of the human cHa-ras1 proto-oncogene.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society - 1 Jan 1990
Uitterlinden A G, Vijg J
Abstract excerpt
Activation of ras proto-oncogenes frequently involves point mutations at different sites in the gene. Here we describe the application of denaturing gradient gel electrophoresis to identify and characterize such mutations in the cHa-ras1 proto-oncogene. We calculated a melting map of the cHa-ras1...
Topics
- Chromosome Mapping
- Electrophoresis, Polyacrylamide Gel
- Exons
- Humans
- Mutation
- Nucleic Acid Denaturation
- Nucleic Acid Heteroduplexes
- Proto-Oncogene Mas
- Proto-Oncogene Proteins p21(ras)
- Proto-Oncogenes
