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Article

Denaturing gradient gel electrophoretic analysis of the human cHa-ras1 proto-oncogene.

Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society - 1 Jan 1990

Uitterlinden A G, Vijg J

Abstract excerpt

Activation of ras proto-oncogenes frequently involves point mutations at different sites in the gene. Here we describe the application of denaturing gradient gel electrophoresis to identify and characterize such mutations in the cHa-ras1 proto-oncogene. We calculated a melting map of the cHa-ras1 gene and designed optimal conditions to separate mutant from wild type sequences in the first exon. As an example we...

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PMID: 2098100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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