Article
Genetic aberrations of the K-ras proto-oncogene in bladder cancer in Kashmiri population.
Urology journal - 1 Jan 2010
Nanda Mahoor S, Sameer A Syed, Syeed Nidda, Shah Zaffar A, Murtaza Imtiyaz, Siddiqi Mushtaq A, Ali Arif
Abstract excerpt
PURPOSE: To assess the frequency of specific point mutations in the K-ras gene in a group of Kashmiri patients with bladder cancer. MATERIALS AND METHODS: We analyzed the incidence of K-ras exon 1 gene mutations in tumors and surgical margins in 60 patients with transitional cell carcinoma of varied clinical stages and histological grades using the polymerase chain reaction-single strand conformation polymorphism...
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