Article
HLA-DR types in Japanese schizophrenics: analysis by group-specific PCR amplification.
Schizophrenia research - 1 Dec 1994
Sasaki T, Kuwata S, Dai X Y, Nanko S, Hattori M, Yanagisawa M, Tokunaga K, Kazamatsuri H, Juji T
Abstract excerpt
An association of HLA-DR8 and DR1 with DSM-III schizophrenia has been reported in Japan (Miyanaga et al. (1984) Biol. Psychiatr. 19, 121-129). To further investigate this preliminary finding, we compared HLA-DR types in 44 unrelated Japanese schizophrenics (DSM-III-R) with those in 51 unrelated, healthy Japanese volunteers. Group-specific PCR amplification was used in the determination of HLA-DR in the patients....
Topics
- Adult
- Alleles
- Base Sequence
- Cross-Cultural Comparison
- Female
- Gene Frequency
- Genetics, Population
- HLA-DR Antigens
- HLA-DR1 Antigen
- Humans
- Japan