Article
Association study of HLA-A gene and schizophrenia in Han Chinese from Taiwan.
Progress in neuro-psychopharmacology & biological psychiatry - 12 Dec 2008
Chao Yu-Lin, Shen Yu-Chih, Liao Ding-Lieh, Chen Jen-Yeu, Wang Ying-Chieh, Lai I-Ching, Liou Ying-Jay, Chen Chia-Hsiang
Abstract excerpt
Dysregulation of the immune response has been proposed as a precipitating factor of schizophrenia, and human leukocyte antigens (HLA) play a critical role in regulating the cascade of immunological reaction. Hence, many studies have investigated the relationship between the HLA system and schizophrenia. HLA is a complex gene family that contains several highly polymorphic genes, while the HLA-A gene is the most...
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