Article
Further evidence for an association between schizophrenia and the HLA DQB1 gene locus.
Schizophrenia research - 1 Dec 1995
Nimgaonkar V L, Rudert W A, Zhang X R, Tsoi W F, Trucco M, Saha N
Abstract excerpt
A case-control study was conducted in Singapore, in order to examine a proposed association between schizophrenia and the HLA DQB1 gene locus. The probands were male inpatients of Chinese ethnicity with schizophrenia (ICD-10 criteria, n = 102) and the controls were adults matched for gender and ethnicity (n = 111). Polymorphisms of the HLA DQB1 gene were examined using molecular typing by reverse dot-blotting...
Topics
- Adult
- Alleles
- Case-Control Studies
- China
- Chromosome Mapping
- Gene Frequency
- Genetic Markers
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Male
- Middle Aged
- Models, Genetic
- Odds Ratio
- Polymorphism, Genetic
- Schizophrenia
- Schizophrenic Psychology
- Singapore
