Article
Evidence supporting an association between the DRB1 gene and schizophrenia in Japanese.
Schizophrenia research - 27 Jul 1998
Arinami T, Otsuka Y, Hamaguchi H, Itokawa M, Aoki J, Shibuya H, Okubo Y, Iwawaki A, Ota K, Enguchi H, Tagaya H, Yano S, Shimizu H, Toru M
Abstract excerpt
The authors attempted a replication of earlier studies that detected an association of HLA-DR4 and DR1 with schizophrenia. Japanese patients with schizophrenia (n = 266, DSM-III-R criteria) and Japanese controls (n = 283) were genotyped for DR1 and DR4 alleles using a combination of group-specifi...
Topics
- Female
- Genotype
- HLA-DR Antigens
- HLA-DR1 Antigen
- HLA-DR4 Antigen
- HLA-DRB1 Chains
- Humans
- Japan
- Male
- Middle Aged
- Phenotype
- Schizophrenia
