Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.

doi:10.1128/MCB.15.4.2117

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Article

Separate domains of the Ran GTPase interact with different factors to regulate nuclear protein import and RNA processing.

Molecular and cellular biology - 1 Apr 1995

Ren M, Villamarin A, Shih A, Coutavas E, Moore M S, LoCurcio M, Clarke V, Oppenheim J D, D'Eustachio P, Rush M G

Abstract excerpt

The small Ras-related GTP binding and hydrolyzing protein Ran has been implicated in a variety of processes, including cell cycle progression, DNA synthesis, RNA processing, and nuclear-cytosolic trafficking of both RNA and proteins. Like other small GTPases, Ran appears to function as a switch:...

Topics

Amino Acid Sequence
Animals
Base Sequence
Biological Transport
Cell Cycle Proteins
DNA-Binding Proteins
Fungal Proteins
GTP Phosphohydrolases
GTPase-Activating Proteins
Guanine Nucleotide Exchange Factors
Guanosine Triphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Mice

Mitosis

Models, Biological

Molecular Sequence Data

Mutation

Nuclear Proteins

Source

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Identifiers

PMID: 7891706
DOI: 10.1128/MCB.15.4.2117
PMCID: PMC230439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7891706-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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