Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus.

doi:10.1093/emboj/16.20.6237

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Article

Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus.

The EMBO journal - 15 Oct 1997

Schlenstedt G, Smirnova E, Deane R, Solsbacher J, Kutay U, Görlich D, Ponstingl H, Bischoff F R

Abstract excerpt

Gsp1p, the essential yeast Ran homologue, is a key regulator of transport across the nuclear pore complex (NPC). We report the identification of Yrb4p, a novel Gsp1p binding protein. The 123 kDa protein was isolated from Saccharomyces cerevisiae cells and found to be related to importin-beta, the...

Topics

Amino Acid Sequence
Biological Transport
Carrier Proteins
Cell Compartmentation
Cell Nucleus
Cloning, Molecular
Cytosol
DNA-Binding Proteins
Fungal Proteins
GTP Phosphohydrolases
GTP-Binding Proteins
Genes, Fungal
Genes, Reporter
Guanosine Triphosphate
Immunohistochemistry

Source

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Identifiers

PMID: 9321403
DOI: 10.1093/emboj/16.20.6237
PMCID: PMC1326308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9321403-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Molecular Sequence Data

Monomeric GTP-Binding Proteins

Mutation