Article
The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster.
Immunity - 1 May 1994
Lynch D H, Watson M L, Alderson M R, Baum P R, Miller R E, Tough T, Gibson M, Davis-Smith T, Smith C A, Hunter K
Abstract excerpt
The gene for the mouse Fas ligand was cloned and its chromosomal position determined. Fasl was tightly linked to gld (no crossovers in 567 meiotic events) on mouse chromosome 1 and closely linked with a novel member of the same TNF family of ligands, the Ox40 ligand (Ox40l, 1 crossover in 567 mei...
Topics
- Amino Acid Sequence
- Animals
- Autoimmune Diseases
- Base Sequence
- Cell Line
- Chromosome Mapping
- Cloning, Molecular
- DNA
- Fas Ligand Protein
- Genetic Linkage
- Membrane Glycoproteins
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Molecular Sequence Data
- Multigene Family
- Phenotype
- Point Mutation