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Article

Allele-specific PCR analysis for detection of the gld Fas-ligand point mutation.

Journal of immunological methods - 15 Dec 1997

Hoek R M, Kortekaas M C, Sedgwick J D

Abstract excerpt

The discovery of a naturally occurring missense point mutation in the gene encoding Fas-ligand (FasL/CD95L) in generalized lymphoproliferative disease (gld) mice has lead to the characterization of FasL as an important mediator of apoptosis. Further analysis of FasL function can be facilitated by...

Topics

Alleles
Animals
DNA Mutational Analysis
Fas Ligand Protein
Ligands
Lymphoproliferative Disorders
Membrane Glycoproteins
Mice
Point Mutation
Polymerase Chain Reaction
fas Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9502590
DOI: 10.1016/s0022-1759(97)00185-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9502590-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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