A linkage map of mouse chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation.

doi:10.1007/BF00302874

Back to search

Article

A linkage map of mouse chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992

Watson M L, D'Eustachio P, Mock B A, Steinberg A D, Morse H C, Oakey R J, Howard T A, Rochelle J M, Seldin M F

Abstract excerpt

An interspecific backcross was used to define a high resolution linkage map of mouse Chromosome (Chr) 1 and to analyze the segregation of the generalized lymphoproliferative disease (gld) mutation. Mice homozygous for gld have multiple features of autoimmune disease. Analysis of up to 428 progeny...

Topics

Animals
Autoimmunity
Chromosome Mapping
Crosses, Genetic
Female
Male
Mice
Mice, Inbred C3H
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.