Article
A linkage map of mouse chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1992
Watson M L, D'Eustachio P, Mock B A, Steinberg A D, Morse H C, Oakey R J, Howard T A, Rochelle J M, Seldin M F
Abstract excerpt
An interspecific backcross was used to define a high resolution linkage map of mouse Chromosome (Chr) 1 and to analyze the segregation of the generalized lymphoproliferative disease (gld) mutation. Mice homozygous for gld have multiple features of autoimmune disease. Analysis of up to 428 progeny from the backcross [(C3H/HeJ-gld x Mus spretus)F1 x C3H/HeJ-gld] established a map that spans 77.6 cM and includes 56...
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