Article
Cystic fibrosis-related diabetes is associated with HLA DQB1 alleles encoding Asp-57- molecules.
Journal of clinical immunology - 1 Nov 1994
Carrington M, Krueger L J, Holsclaw D S, Iannuzzi M C, Dean M, Mann D
Abstract excerpt
The incidence of insulin-dependent diabetes in individuals with cystic fibrosis is nearly 100 times greater than in the general population. In the latter group, strong associations with specific HLA DQA1 and DQB1 alleles have been observed. To determine if a similar distribution of alleles occurs in cystic fibrosis patients with diabetes, a cohort of these individuals was typed for DQA1 and DQB1 alleles. HLA...
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