Article
Mutation of the conserved Gly83 and Gly94 in Escherichia coli elongation factor Tu. Indication of structural pivots.
European journal of biochemistry - 15 Feb 1995
Kjaersgård I V, Knudsen C R, Wiborg O
Abstract excerpt
Elongation factor Tu from Escherichia coli cycles between an active conformation where GTP is bound, and an inactive conformation where GDP is bound. Between the two conformations, elongation factor Tu undergoes major structural changes. The aim of this work has been to reveal the role of two ver...
Topics
- Base Sequence
- GTP Phosphohydrolase-Linked Elongation Factors
- Guanosine Diphosphate
- Guanosine Triphosphate
- Molecular Sequence Data
- Mutation
- Peptide Elongation Factor Tu
- Protein Biosynthesis
- Structure-Activity Relationship