Article
Bacterial elongation factors EF-Tu, their mutants, chimeric forms, and domains: isolation and purification.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 15 Apr 2007
Jonák J
Abstract excerpt
Prokaryotic elongation factors EF-Tu form a family of homologous, three-domain molecular switches catalyzing the binding of aminoacyl-tRNAs to ribosomes during the process of mRNA translation. They are GTP-binding proteins, or GTPases. Binding of GTP or GDP regulates their conformation and thus their activity. Because of their particular structure and regulation, various activities (also outside of the...
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