Article
Elongation factor G with effector loop from elongation factor Tu is inactive in translocation.
FEBS letters - 6 Mar 2002
Kolesnikov Alexander, Gudkov Anatoly
Abstract excerpt
Elongation factors Tu and G (EF-Tu and EF-G) alternately interact with the ribosome during the elongation phase of protein biosynthesis. The function of both factors depends on GTP binding, and the factors are ascribed to a superfamily of G-proteins. All G-proteins contain the effector loop, a structural element that is important for the protein's interaction with its target molecule. In this study the effector...
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