Article
Instability of microsatellites in human gliomas.
Cancer research - 1 Apr 1995
Dams E, Van de Kelft E J, Martin J J, Verlooy J, Willems P J
Abstract excerpt
We have analyzed DNA obtained from 10 glioblastomas multiforme and 6 astrocytomas for microsatellite instability, using 17 different microsatellite loci dispersed over 7 different chromosomes. Six of 16 gliomas showed 1 or more microsatellite alterations in tumor DNA as compared to constitutional DNA. We observed microsatellite instability resulting in allelic shifts in 5 of 10 glioblastomas multiforme but not in...
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