Article
Microsatellite instability in human cancer.
Oncology research - 1 Jan 1995
Speicher M R
Abstract excerpt
Tumorigenesis has made tremendous progress through the recent identification of widespread alterations in tumor genomes, manifested as microsatellite instability. Several genes causing microsatellite instability have already been identified. This was considerably facilitated by the knowledge of homologous DNA mismatch repair genes in bacteria and yeast. Correspondingly, the human genes are also tightly linked to...
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