Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microsatellite Instability in Pediatric and Adult High‐grade Gliomas

8 Feb 2007

Abstract excerpt

About 15% of sporadic gastrointestinal and endometrial tumors show the microsatellite instability (MSI) phenotype because of loss of DNA mismatch repair (MMR) function. The incidence of MSI in tumors of the central nervous system still remains controversial. Previous studies reported a particular high frequency of MSI (approximately 25%) in young patients suffering from high-grade gliomas. Based on these data and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to DNA Repair Mechanisms
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17388945
DOI: 10.1111/j.1750-3639.2007.00049.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite Instability in Pediatric and Adult High‐grade GliomasPMID 17388945Read ↗

Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene InactivationSemantic proximity Read ↗

Microsatellite instability is infrequent in sporadic adult gliomas.Semantic proximity Read ↗

Low-level microsatellite instability phenotype in sporadic glioblastoma multiforme.Semantic proximity Read ↗

Genetic alterations in pediatric high-grade astrocytomas.Semantic proximity Read ↗

Integrated analysis of mismatch repair system in malignant astrocytomas.Semantic proximity Read ↗

The Challenge of Diagnosing Constitutional Mismatch Repair Deficiency Syndrome in Brain Malignancies from Young IndividualsSemantic proximity Read ↗

Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors.Semantic proximity Read ↗

Mismatch-Repair Protein Expression in High-Grade Gliomas: A Large Retrospective Multicenter StudySemantic proximity Read ↗

MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade gliomaSemantic proximity Read ↗

Molecular Characterization of Mismatch Repair Deficient Tumors In Young Jordanian PatientsSemantic proximity Read ↗

Glioblastomas, astrocytomas and oligodendrogliomas linked to Lynch syndromeSemantic proximity Read ↗

Instability of microsatellites in human gliomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.